Basic Information
VIS ID
TVIS10020598
Fusion event
HBV-LOC108254691 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
104
End
1200
Orient
+
Integrated sequence
CCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTT
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80256344/82298468 (Hg38)
End
80257392/82299516 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC108254691
Nearest miRNA
hsa-mir-10226/Upstream/61740; hsa-mir-4525/Downstream/368717;
Nearest TSS
ENST00000595228/Upstream/4752; ENST00000333437/Downstream/18034;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5364, chr17-CpG: 145/Downstream/18815
Upstream sequence
taagagatatagaccagctgtgctatctttttgtggttttcagttctctagtatgttgagcatctttttgtaagtgtacttgccatctgtagatcttctt
Downstream sequence
CCATGGTAAAAATTCAAGAGGTGGAAGGGGCTGGACTATGGGACCAAGGTCAGGTCTTTCTCCTTCGAGGGACCAATGGGTGGCCAGGCTCTGAGGCTGC
Target sequence
gggattacaggtgtgagccaccacgtctggctggaaactcagtttttaaggtgtctctgggaccccttggccaagaggggtcttttcagtagttggggggcttaggatttttttttcttttttttttttgagatggagtctcattgtcacccaggctggagtgcagtggcacgatctcaggtcactgcaacctctgcctcccaggttcaagcgattttcctgcctcagcctcccgagtagctggaattacaggtg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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