Basic Information
VIS ID
TVIS10020603
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1495
End
2543
Orient
-
Integrated sequence
TTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
59709712/59315931 (Hg38)
End
59710760/59316979 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1228/Upstream/1491239; hsa-let-7i/Downstream/2943380;
Nearest TSS
ENST00000382841/Upstream/395292; ENST00000549465/Downstream/94192;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/395260, chr12-CpG: 76/Downstream/278891
Upstream sequence
ctggagtttatactagaaatcattcttataggagaaactagaaaagcaccagagacggtagcaatttttagaagcgggactaacctcagagaagagaggc
Downstream sequence
gactatattcatatttcaacagttttttatgggtactttatgcttgtgtatagttgtatgaaattttgtcatatgtacatatttatgtaactaccaccat
Target sequence
CCAGAGGTGAAGAACAGGCAGCAATTTATAGAAAGTCTTTGATAGGCAATAATGGAGACCAATTAACATACCTCCCCCAGAAGGCAAAAAACTGAAGGtattaagaaaataattttcaaaacttggaaataagaccaaaaaatgcctgtatgttttttaaatgtcatattggagaataatctgagaagtctgcctagacgtcatctgttattcagggacttctaactttgcttgacttattattggttttgattt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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