Basic Information
VIS ID
TVIS10020606
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
42532195/42510645 (Hg38)
End
42533243/42511693 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1343/Upstream/6500441; hsa-let-7a-2/Downstream/1047963;
Nearest TSS
ENST00000527297/Upstream/256933; ENST00000530300/Downstream/800270;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6000178, chr11-CpG: 49/Downstream/800196
Upstream sequence
GTAGTCTAACCAAGGCTACTGAATATGGGTATGTAAATTGTACCCTTCACCAACAGATAGGTCAGAAAAAGAAGAAGACACTCCCTAGAAAGACCCTTCA
Downstream sequence
gattcaattttggaactcatttttggtctgttcagggattcaatatatttctggttcaatctgggggggctgtgtctttccaggaatttacccatttctt
Target sequence
gattgctttgggaagtatggccattttaacaatattgatattgcctatccatgaccatgaaatgattttttacttcttcatatcatctctgatttctttgagcagcgtttggtaattcttgttgtagaggtcttttgcctccagggttacctgtattcttaggtattttatagttttttttggctattgttaatgggattgtattattgacttggctctcagcttggacattgttggtgtataaaaatgctacta
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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