Basic Information
VIS ID
TVIS20000002
Fusion event
HPV-chr3:p11.2 integration
Validated
Yes
Detection method
PCR Ion Torrent Sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical intraepithelial neoplasia (CIN)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26660085
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Host Sequence
Chromosome
chr3
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
88525362/88393522 (Hg38)
End
88525362/88393522 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/1167245; hsa-mir-12124/Downstream/7966442;
Nearest TSS
ENST00000440867/Upstream/54999; ENST00000452448/Downstream/714002;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/243159, chr3-CpG: 41/Downstream/720963
Upstream sequence
gataatttgttgaatcaaaatgggggaatataaacagacgtgaagttgatataaataaataatatagacagagtggatcgatatagataaatggatgtgt
Downstream sequence
acatacacatacacatatttatgtacttagggtaatggtgccatagattcaacaatattttaaagacaaagtgtaagtgcaatagcagagtgacatatac
Reference
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.
Curate