VISDB Viral Integration Site DataBase

VIS ID

TVIS20000003

Fusion event

HPV-chr9:q33.3 integration

Validated

Yes

Detection method

PCR Ion Torrent Sequencing

Data source

Curated

Sample type

Disease

Cervical intraepithelial neoplasia (CIN)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Chromosome

chr9

Cytoband

q33.3

Reference genome

Start

End

126313825/124511725 (Hg38)

Location type

Intronic

Target gene

NR5A1 ; NR6A1

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-9-5p ; hsa-mir-181a-5p ; hsa-mir-218-5p ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-346 ; hsa-mir-6508-3p ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-646 ; hsa-mir-4257 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-let-7e-5p ; hsa-mir-98-5p ; hsa-let-7c-5p ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7a-5p ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7b-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-4440 ; hsa-mir-4493 ; hsa-mir-605-3p ; hsa-mir-4272 ; hsa-mir-5011-5p ; hsa-mir-15a-3p ; hsa-mir-3664-5p ; hsa-mir-1277-5p ; hsa-mir-4753-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-1289 ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-1972 ; hsa-mir-2467-3p ; hsa-mir-3158-5p ; hsa-mir-3174 ; hsa-mir-3678-3p ; hsa-mir-3927-3p ; hsa-mir-4496 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4691-5p ; hsa-mir-4731-5p ; hsa-mir-4736 ; hsa-mir-486-3p ; hsa-mir-561-5p ; hsa-mir-6073 ; hsa-mir-654-3p ; hsa-mir-6721-5p ; hsa-mir-6830-5p ; hsa-mir-6831-5p ; hsa-mir-7844-5p ; hsa-mir-921

Nearest miRNA

hsa-let-7a-1/Upstream/1026103; hsa-mir-12126/Downstream/180717;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/6345, chr9-CpG: 144/Downstream/258036

Upstream sequence

CCTCTCCACCCTGCCAGAGCCCCTGGGTGGCCTGTCCTTTCCTTCAAGCTCTAGCCCTGGTGGTCCCAGGCCACTAGACCTACCCAGAGGGGAAAGCAAA

Downstream sequence

GGAGGGCTGTAGTCCTGACTCAGGCGCCCCCAACCTCCCTCCCCAGGCAAACAAAGCCCAGGGTCTCTCTCCTAACTGGGGACTTTCCCAAAGTGCCAGG