Basic Information
VIS ID
TVIS20000011
Fusion event
HPV-chr20:q13.13 integration
Validated
Yes
Detection method
APOT and sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical intraepithelial neoplasia (CIN)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26660085
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
NCBI36/hg18
Start
48435994/50386050 (Hg38)
End
48435994/50386050 (Hg38)
Nearest miRNA
hsa-mir-103a-2/Upstream/522097; hsa-mir-1-1/Downstream/199736;
Nearest TSS
ENST00000382410/Upstream/64708; ENST00000541713/Downstream/124271;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/42214, chr20-CpG: 84/Downstream/124030
Upstream sequence
CCTGTGCAATGAGTGTGAGAGGTGGAAGaggctacaatatgggcgtggcttcctccctgagtgaagtagggagccatgggagggttttgagcagaggagg
Downstream sequence
gccctgccctgactttgatttttacagaatccctctggctacttgtggataacagtcttcatgggggccaggaagcggagaagtctgctgcaggaagcga
Reference
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.
Curate