Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20000014
Fusion event
HPV-ITPR1 integration
Validated
Yes
Detection method
PCR Ion Torrent Sequencing
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr3
Cytoband
p26.2
Reference genome
Start
End
4804305/4787621 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-424-5p ; hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-128-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-4328 ; hsa-mir-4803 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-494-3p ; hsa-mir-34c-5p ; hsa-mir-34b-3p ; hsa-mir-449a ; hsa-mir-448 ; hsa-mir-3163
Nearest miRNA
hsa-let-7g/Downstream/462556;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/293938, chr3-CpG: 67/Downstream/80657
Upstream sequence
ctgtcaatactggaggaaaaaaaaaaaaaagccaggcgtgaaggtgcgtgcctgtaatcccagctactctggaggctgaggcaggagaatcacttaaacc
Downstream sequence
caggaggcagaggttgcagtgagccaagatcgcaccactgcactctgtcctgggtgacagagcaagactcctgactctgtctcaaaaaaataaaaattaa
Reference
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.