Basic Information
VIS ID
TVIS20000015
Fusion event
HPV-chr13:q22.1 integration
Validated
Yes
Detection method
APOT and sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26660085
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Host Sequence
Chromosome
chr13
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
72885297/73413159 (Hg38)
End
72885297/73413159 (Hg38)
Fragile sites / regions
FRA13E
Nearest miRNA
hsa-mir-1297/Upstream/7194835; hsa-mir-1267/Downstream/4284853;
Nearest TSS
ENST00000623511/Upstream/338144; ENST00000430033/Downstream/133682;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/352927, chr13-CpG: 31/Downstream/720813
Nearby gene
MARK2P12(-4834) ;
Upstream sequence
tcccaccttgctctcccaaattgttgggattacaggtgtgagccactgtgcccagccTGCACATTGATTCTGAATCATCATTGATGACTAAGTGTTTCTA
Downstream sequence
GCATTTTTATATATTTTGAGTTTGCATCATCCCATTCTACAATCACAATTCTTTAATTAAATGGAGATCACCCAATGACACAGAAGAATGCTTGAATTAG
Reference
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.
Curate