Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20000016
Fusion event
HPV-BCL11B integration
Validated
Yes
Detection method
PCR Ion Torrent Sequencing
Data source
Curated
Sample type
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
Start
End
98775862/99239772 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-128-3p ; hsa-mir-183-5p ; hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-203a-3p ; hsa-mir-137 ; hsa-mir-552-5p ; hsa-mir-218-5p ; hsa-mir-6508-3p ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-3926 ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-1224-3p ; hsa-mir-1273d ; hsa-mir-4311 ; hsa-mir-944 ; hsa-mir-367-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-363-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-330-3p ; hsa-mir-8070 ; hsa-mir-8066 ; hsa-mir-3119 ; hsa-mir-4713-5p ; hsa-mir-642a-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6832-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-3938
Nearest miRNA
hsa-mir-1260a/Upstream/4101786; hsa-mir-1185-1/Downstream/869647;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/63342, chr14-CpG: 133/Downstream/5730
Nearest cancer related gene
BCL11B(OG, No orient, 0)
Upstream sequence
TGCCTGACCTTTGAGGAATGACCCGGAAAACACTGAATCCTGACACGTGTTAAGAATCTGGCCCTCCCTAAAACATGTTTACAAACTGGGGAGTTCAGGA
Downstream sequence
AGTTGTGGTTCCAAGGTCCCATGAACTCCAATGCTGGCTTTTGCTCAACGGCCATGTACAGACAGTGCAATGGAATAAACAGAAGGAGGAAGGCTGAGCT
Reference
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.