Fusion event
HPV-chr9:q34.3 integration
Detection method
APOT and sequencing
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
End
138625713/136611440 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/65181; hsa-mir-126/Downstream/59162;
Upstream sequence
GGCCACTCATGTGGAGTCCAGGGGACCCAGGGAGCTCCAGGAGGCCTCTGGAACCCTCCAGAACCTTCCAGAACTTCACACTTGAATTTTGTTCTGTCCC
Downstream sequence
AGGCAGGTTCTCCAGCCTCAGGTCCAATGGCCAACTCATGCCCAGGGCAGGCCCAGTGTGGGGCTTGGGCGCCGAGGGAGGGACCGCACACCTTGAGTTC
Bodelon, C., et al. Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis.2016, 37(2): 188-196.