VISDB Viral Integration Site DataBase

VIS ID

TVIS20000027

Fusion event

HPV-chr11:q13.1 integration

Validated

Yes

Detection method

PCR Ion Torrent Sequencing

Data source

Curated

Sample type

Disease

Cervical carcinoma (CC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Chromosome

chr11

Cytoband

q13.1

Reference genome

Start

End

66165789/66641742 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

RBM14 ; RBM4 ; RBM4B

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-424-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-let-7e-5p ; hsa-let-7e-5p ; hsa-mir-3674 ; hsa-mir-5699-5p ; hsa-mir-218-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-548av-3p ; hsa-mir-7151-3p ; hsa-mir-6807-5p ; hsa-mir-5095 ; hsa-mir-6735-3p ; hsa-mir-214-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-6748-3p ; hsa-mir-3065-3p ; hsa-mir-6504-3p ; hsa-mir-449b-3p ; hsa-mir-6871-3p ; hsa-mir-941 ; hsa-mir-4438 ; hsa-mir-5096 ; hsa-mir-5089-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-4755-3p ; hsa-mir-1273f ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-505-5p ; hsa-mir-769-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-498 ; hsa-mir-3124-5p ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-1247-3p ; hsa-mir-17-3p ; hsa-mir-25-5p ; hsa-mir-3160-3p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-4459 ; hsa-mir-4487 ; hsa-mir-485-5p ; hsa-mir-5186 ; hsa-mir-558 ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6500-3p ; hsa-mir-658 ; hsa-mir-6884-5p ; hsa-mir-4477a

Nearest miRNA

hsa-mir-10392/Upstream/992489; hsa-let-7a-2/Downstream/292692;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/2522, chr11-CpG: 47/Downstream/1712

Nearest cancer related gene

RBM4(TSG, No orient, 0)

Upstream sequence

ATCCTTATATAAAACTCTGGGTGTCTGAACCCTAGGTCCCCTGACACTAACCTATGCTTAGTTATTTTTACCTTATTTTATGTAATATTGGCGTTTCTCA

Downstream sequence

TTTCTTAATACTGTTCTGGTAGAATTATAGATGTATATTGATGAGCAGTAGTTATTAGGGTGGTCTTTTTTCCTTTCCGTTTCTCAGTGTTGGGTATCTT