Basic Information
VIS ID
TVIS20000038
Fusion event
HPV-LOC107984285 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E2
Start
2863
Integrated sequence
AAAAGGTGATGCTAATACTTTAAAATGTTTAAGATATAGATTTAAAAAGCATTGTACATTGTATACTGCAGTGTCGTCTACATGGCATTGGACAGGACAT| |AATGTAAAACATAAAAGTGCAATTGTTACACTTACATATGATAGTGAATGGCAACGTGACCAATTTTTGTCTCAAGTTAAAATACCAAAAACTATTACAG
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
1019766/973826 (Hg38)
End
1019766/973826 (Hg38)
Location type
Intronic
Target gene
LOC107984285
Nearest miRNA
hsa-mir-5699/Upstream/332048; hsa-mir-107/Downstream/1102193;
Nearest TSS
ENST00000439456/Upstream/40800; ENST00000360059/Downstream/14193;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/13941, chr10-CpG: 60/Downstream/1875
Upstream sequence
ttcctaagccgtgcaacaattaatttgaaagaatgtaaaatgatgcacagagaagaatggaaaatgtggagtgtaagatacacatggagccgagtgaaca
Downstream sequence
AAAGAGCAGTGTTTTTCCCATTACCTATTCCAGAACATGTCACCAGAGAATACTTGACAAGTCAACATGGTGGGAATGGCCCTATCATACCCATATGGAG
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
Curate