CAGE1 _CESC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS20000049
Fusion event
HPV-CAGE1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E2/E4
Start
3344
Integrated sequence
GTACATAATGTAATTGTTACATATAATTGTTGTATACCATAACTTACTATTTTTTCTTTTTTATTTTCATATATAATTTTTTTTTTTGTTTGTTTGTTTG| |TTTTTTAATAAACTGTTATTACTTAACAATGCGACACAAACGTTCTGCAAAACGCACAAAACGTGCATCGGCTACCCAACTTTATAAAACATGCAAACAG
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
7327990/7327757 (Hg38)
End
7327990/7327757 (Hg38)
Location type
Intronic
Target gene
CAGE1
miRNAs that regulate target gene
hsa-mir-7-5p
Nearest miRNA
hsa-mir-3691/Upstream/1158322; hsa-mir-10398/Downstream/3111960;
Nearest TSS
ENST00000381078/Upstream/14526; ENST00000475351/Downstream/19689;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/14334, chr6-CpG: 65/Downstream/61644
Upstream sequence
CTTTTTATCCCTGGCCTATGTTTCTCCCACCCTCCTTccttaaccctaaccccaaccttaaccctaaccctaaccctaaccctaaccctaaccctaacct
Downstream sequence
ccgtctctactaaaaatacaaaattagctaggcgtggtggtacctgcctgtaaccccagctactcgggaggctgaggcaggagaatcacttgaaccccgg
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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