Basic Information
VIS ID
TVIS20000050
Fusion event
HPV-chr3:q25.31 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E5
Start
3883
Integrated sequence
TCAACTGATACCACACCTGCTATATTAGATATTAATAATACTGTTACTACTGTTACTACACATAATAATCCCACTTTCACTGACCCATCTGTATTGCAGC| |CTCCAACACCTGCAGAAACTGGAGGGCATTTTACACTTTCATCATCCACTATTAGTACACATAATTATGAAGAAATTCCTATGGATACATTTATTGTTAG
Host Sequence
Chromosome
chr3
Cytoband
q25.31
Reference genome
GRCh37/hg19
Start
156990726/157272937 (Hg38)
End
156990726/157272937 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
LOC101928236 ; VEPH1
Nearest miRNA
hsa-let-7g/Upstream/5706942; hsa-mir-1224/Downstream/2009709;
Nearest TSS
ENST00000440867/Upstream/109485; ENST00000295927/Downstream/91544;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/97690, chr3-CpG: 59/Downstream/164541
Upstream sequence
TTTCCTGGTTTAAAATTTGCAAAAATTATTTTTTTTTGAAGAAAGATTCAGTGATACTAATATGTCTAATGATTGCTAAGCACAACCACAGACACTAGCA
Downstream sequence
CGCCTACAACTTGCCAATTTGCAGGTAGTTTGTACTACAGACATGGTGGTGATTCCCTTATTATGGAAGAAGGGTAGAAAGGAGTTAGAGGGGGAAAACC
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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