Basic Information
VIS ID
TVIS20000051
Fusion event
HPV-chr12:p12.3 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
L2
Start
4393
Integrated sequence
AATAAACAAACACTACGTACTCGTAGTGGAAAATCTATAGGTGCTAAGGTACATTATTATTATGATTTAAGTACTATTGATCCTGCAGAAGAAATAGAAT| |TACAAACTATAACACCTTCTACATATACTACCACTTCACATGCAGCCTCACCTACTTCTATTAATAATGGATTATATGATATTTATGCAGATGACTTTAT
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
17224129/17071195 (Hg38)
End
17224129/17071195 (Hg38)
Nearest miRNA
hsa-mir-1244-3/Upstream/4155277; hsa-let-7i/Downstream/602104;
Nearest TSS
ENST00000382841/Upstream/377395; ENST00000539105/Downstream/518062;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1159595, chr12-CpG: 131/Downstream/2058196
Nearby gene
RNU6-837P(+203) ;
Upstream sequence
gctcaagccatcctcccacatcagcctcccaagtagataggtgcaccaccatgtccgggtaattttttgtatttttggtaaatatggggttttgccatgt
Downstream sequence
aaaaaagagacaaagtccaggtactcaaggaacttCTCATCACTTTGTCATTTTCTTGAATCAACATGCTCCACGATAGTATAAAGCCTTCCCTTTTCAT
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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