Basic Information
VIS ID
TVIS20000053
Fusion event
HPV-chr20:q11.22 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
L2
Start
4453
Integrated sequence
TATGATTTAAGTACTATTGATCCTGCAGAAGAAATAGAATTACAAACTATAACACCTTCTACATATACTACCACTTCACATGCAGCCTCACCTACTTCTA| |TTAATAATGGATTATATGATATTTATGCAGATGACTTTATTACAGATACTTCTACAACCCCGGTACCATCTGTACCCTCTACATCTTTATCAGGTTATAT
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
32472391/33884585 (Hg38)
End
32472391/33884585 (Hg38)
Nearest miRNA
hsa-mir-103a-2/Upstream/1646738; hsa-mir-1-1/Downstream/164534;
Nearest TSS
ENST00000382410/Upstream/73281; ENST00000413297/Downstream/107233;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/21626, chr20-CpG: 132/Downstream/108408
Upstream sequence
ATTCTCGAATTTACCGTGGTCTGAACTTCAACATCGAGGTTGCTATTTCTGTTTTATCATTGACTCAACTTCAAGCCAGGTTATCAGGGTAAGTTATTCC
Downstream sequence
Ataaaatccaaactccttcccgtggcctacaaagccctgctgaccccgtccctgcctgccatcacccccaacctcaggtccagccagtgtggccttcttg
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
Curate