Basic Information
VIS ID
TVIS20000057
Fusion event
HPV-chr20:q11.22 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
L1
Start
6618
Integrated sequence
ATTTGCTACATCCTGTTTTTGTTTTATATATACTATATTTTGTAGCGCCAGCGGCCATTTTGTAGCTTCAACCGAATTCGGTTGCATGCTTTTTGGCACA| |AAATGTGTTTTTTTAAATAGTTCTATGTCAGCAACTATGGTTTAAACTTGTACGTTTCCTGCTTGCCATGCGTGCCAAATCCCTGTTTTCCTGACCTGCA
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
32506420/33918614 (Hg38)
End
32506420/33918614 (Hg38)
Nearest miRNA
hsa-mir-103a-2/Upstream/1680767; hsa-mir-1-1/Downstream/130505;
Nearest TSS
ENST00000382410/Upstream/107310; ENST00000413297/Downstream/73204;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/55655, chr20-CpG: 132/Downstream/74379
Nearby gene
TPM3P2(-5191) ;
Upstream sequence
ggtctcaaactgctgggctcaagtgatcctctcgcctcggcctcccaaaatgctgggataacaggcgtgagccactgtgcccagggctggcctctcttgg
Downstream sequence
ACTGGAAGTGTTGGCATTTGCCTTTCGCCCACCATAGCAATTCTCTATCCTCCTCCTCACCCTTGAAGGGACCAGCCAGGCCCTCTTTCCCACTTTTGGA
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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