Basic Information
VIS ID
TVIS20000066
Fusion event
HPV-chr11:p15.4 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E1
Start
1043
Integrated sequence
CAGCAGCAGCATTATATTGGTATAAAACAGGTATATCAAATATTAGTGAAGTGTATGGAGACACGCCAGAATGGATACAAAGACAAACAGTATTACAACA| |TAGTTTTAATGATTGTACATTTGAATTATCACAGATGGTACAATGGGCCTACGATAATGACATAGTAGACGATAGTGAAATTGCATATAAATATGCACAA
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
9292546/9270999 (Hg38)
End
9292546/9270999 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/180620; hsa-let-7a-2/Downstream/1237271;
Nearest TSS
ENST00000527297/Upstream/5609; ENST00000630083/Downstream/17074;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/5455, chr11-CpG: 80/Downstream/43184
Nearby gene
DENND5A(-5673) ; TRL-CAA5-1(+4244) ;
Upstream sequence
gggctctcttttatttccatatgaattttagaatactttttttttctaattctgtgaagaatgtcataggtagtttcataggaatagcactgaaaattta
Downstream sequence
tatgttggtcaggctggtcttgaactcctaacctcaggtgatccacctgcctcggccttccaaCACACTGAttttttaaaatctactttgcggaggtata
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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