Basic Information
VIS ID
TVIS20000087
Fusion event
HPV-chr1:p35.2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
LCR
Start
7567
Integrated sequence
AGCCACTGTGTCCTGAAGAAAAGCAAAGACATCTGGACAAAAAGCAAAGATTCCATAATATAAGGGGTCGGTGGACCGGTCGATGTATGTCTTGTTGCAG| |ATCATCAAGAACACGTAGAGAAACCCAGCTGTAATCATGCATGGAGATACACCTACATTGCATGAATATATGTTAGATTTGCAACCAGAGACAACTGATC
Host Sequence
Chromosome
chr1
Cytoband
p35.2
Reference genome
GRCh37/hg19
Start
31618653/31145806 (Hg38)
End
31618653/31145806 (Hg38)
Nearest miRNA
hsa-mir-12136/Upstream/406574; hsa-mir-101-1/Downstream/612854;
Nearest TSS
ENST00000473358/Upstream/79815; ENST00000479629/Downstream/35870;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/79715, chr1-CpG: 42/Downstream/9447
Nearby gene
LOC107984935(+9261) ;
Upstream sequence
AGCCCAATGTTTCTGCAAGTCATTTCACAGGCCACACTCTCCCACCCTTTGGCAATGTATTTTCATAAGACTCCAGTGGTTACTCGATATAAATGTTTAG
Downstream sequence
TTGGCTCATTTTTCTTTCTTTTGCTCTTGCCTAGCATTGAGTATATCGATGGCATAAGATTTCAAATGGTTATGCCAGCTCATTGGCTTTTCTTCTCCAA
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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