Basic Information
VIS ID
TVIS20000116
Fusion event
HPV-chr7:q31.31 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
L2
Start
4279
Integrated sequence
AGTAATGATAATAGTATTAATATAGCTCCAGATCCTGACTTTTTGGATATAGTTGCTTTACATAGGCCAGCATTAACCTCTAGGCGTACTGGCATTAGGT| |ACAGTAGAATTGGTAATAAACAAACACTACGTACTCGTAGTGGAAAATCTATAGGTGCTAAGGTACATTATTATTATGATTTAAGTACTATTGATCCTGC
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
GRCh37/hg19
Start
117974122/118334068 (Hg38)
End
117974122/118334068 (Hg38)
Nearest miRNA
hsa-mir-10525/Upstream/1313749; hsa-mir-10399/Downstream/8724020;
Nearest TSS
ENST00000635602/Upstream/94093; ENST00000421825/Downstream/1573307;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/119401, chr7-CpG: 93/Downstream/1938718
Upstream sequence
aggtgggcggatcacgaggtcaggagatcgagaccatcccggctaacatggtgaaaccctgtctctactaaaaatacaaaaaaacagccgagtgtggtgg
Downstream sequence
CAGCAAATGATATTTTTAGGAAAGAAGTCAATGATGTTCAGAACTGAATTTGGATGCTACTTGACAGGATTTCACTATGGACAGAAGATCTTGACAAATA
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
Curate