Basic Information
VIS ID
TVIS20000118
Fusion event
HPV-chr14:q31.3 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
L2
Start
5045
Integrated sequence
AACAAAATATTAGTTCCTAAAGTATCAGGATTACAATACAGGGTATTTAGAATACATTTACCTGACCCCAATAAGTTTGGTTTTCCTGACACCTCATTTT| |ATAATCCAGATACACAGCGGCTGGTTTGGGCCTGTGTAGGTGTTGAGGTAGGTCGTGGTCAGCCATTAGGTGTGGGCATTAGTGGCCATCCTTTATTAAA
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
86378287/85911943 (Hg38)
End
86378287/85911943 (Hg38)
Nearest miRNA
hsa-mir-1260a/Upstream/8645653; hsa-mir-1185-1/Downstream/8036283;
Nearest TSS
ENST00000550708/Upstream/288253; ENST00000554647/Downstream/22767;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/377809, chr14-CpG: 87/Downstream/2080609
Upstream sequence
taactggttatttttaaaaagaactgtaatgtaagacaagtaagaaagtaaaaaatgttataaatgggctgtgtaagtggttataaggtataagaaacag
Downstream sequence
cgatgaatgtcagaaataggcttttactgtaaaaagtattcaagatatggagactaaaaatatgtatcaaagagttttctcacacttccatgaaaacctc
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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