Basic Information
VIS ID
TVIS20000119
Fusion event
HPV-LOC105373727 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E7
Start
777
Integrated sequence
TAAAAGTAATAAATCAACGTGTTGCGATTGGTGTATTGCTGCATTTGGACTTACACCCAGTATAGCTGACAGTATAAAAACACTATTACAACAATATTGT| |TTATATTTACACATTCAAAGTTTAGCATGTTCATGGGGAATGGTTGTGTTACTATTAGTAAGATATAAATGTGGAAAAAATAGAGAAACAATTGAAAAAT
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
164142942/163286432 (Hg38)
End
164142942/163286432 (Hg38)
Location type
Intronic
Target gene
LOC105373727
Nearest miRNA
hsa-mir-128-1/Upstream/2878550; hsa-mir-10b/Downstream/5296511;
Nearest TSS
ENST00000437798/Upstream/447702; ENST00000628960/Downstream/449552;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/941917, chr2-CpG: 28/Downstream/61798
Upstream sequence
taatagatatggtgtatatgaatttcatcaacgcagttttcacaatatctcggggtttcattatggatttaatggagaaataagaactgaataacagaat
Downstream sequence
aaatggtgccaatagaatttctgaaggcttccacaaaccttcgatttgttaagaacaacaacaaaaaagcattatctgtgaagcgcaatatagcaaagtg
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
Curate