Basic Information
VIS ID
TVIS20000124
Fusion event
HPV-chr17:q24.1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.4
Region type
E2/E4
Start
3501
Integrated sequence
AAAACGTGCATCGGCTACCCAACTTTATAAAACATGCAAACAGGCAGGTACATGTCCACCTGACATTATACCTAAGGTTGAAGGCAAAACTATTGCTGAT| |CAAATATTACAATATGGAAGTATGGGTGTATTTTTTGGTGGGTTAGGAATTGGAACAGGGTCGGGTACAGGCGGACGCACTGGGTATATTCCATTGGGAA
Host Sequence
Chromosome
chr17
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
62731602/64735484 (Hg38)
End
62731602/64735484 (Hg38)
Nearest miRNA
hsa-mir-10226/Upstream/234171; hsa-mir-1250/Downstream/45275;
Nearest TSS
ENST00000595228/Upstream/73416; ENST00000577938/Downstream/124143;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/72744, chr17-CpG: 25/Downstream/41306
Upstream sequence
acagtgaaaccccgtctctactaaaaatacaaaaaattagccgggcgtgatgacggacgcctgtaatcccagctactcagaaggctgaagcagaagaatt
Downstream sequence
ggctaatttttatattcttagtagagatggggttttgccatgtagaccaggctggtctcgaattcctgacctcaagtggtatacccacctcggcctccca
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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