Basic Information
VIS ID
TVIS20000131
Fusion event
HPV-LOC105375825 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
NC_001526.2
Region type
E1
Start
2233
Integrated sequence
GAGCAGAAAAAAAACAAATGAGTATGAGTCAATGGATAAAATATAGATGTGATAGGGTAGATGATGG AGGTGATTGGAAGCAAATTGTTATGTTTTTAA| |GGTATCAAGGTGTAGAGTTTATGTCATTTTTAACTGCA TTAAAAAGATTTTTGCAAGGCATACCTAAAAAAAATTGCATATTACTATATGGTGCAGCTA
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
49741244/48828685 (Hg38)
End
49741244/48828685 (Hg38)
Location type
Intronic
Target gene
LOC105375825
Nearest miRNA
hsa-mir-124-1/Upstream/5932410; hsa-mir-10400/Downstream/12886103;
Nearest TSS
ENST00000518652/Upstream/93374; ENST00000522267/Downstream/92744;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/93256, chr8-CpG: 18/Downstream/6151
Upstream sequence
CTTCCTGACTTAGGACATCAAACGTGCAGTGTGAGCTGCGGATCTCACACGAGCCTGGGAAGGCCACAAAGCTCAATGACAAGTTAGACTCAGCATGTTT
Downstream sequence
CTTCATAAGATGTTAGAAAATCTCTATGTCCAATTTAATTATATCTTGGTCTTCTTTTTTGGTTCTTGTGAGGATCTGGGTTTGGAGACCAAAGCACTCC
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
Curate