VISDB Viral Integration Site DataBase

VIS ID

TVIS20000141

Fusion event

HPV-SEMA6D integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Cervical carcinoma (CC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HPV

Subtype

HPV58

Reference genome

Region type

E2

Start

3791

Integrated sequence

CAACAAAAGACGGAAACTCTGTAGTGGTAACACTACGCCTATAATACATTTAAAAGGTGACAGAAACAGT TTAAAATGTTTACGGTACAGATTGCGAA| |AACATAGCGACCACTATAGAGATATATCATCCACCTGGCATT GGACAGGTGCAGGCAATGAAAAAACAGGAATACTGACTGTAACATACCATAGTGAAA

Chromosome

chr15

Cytoband

q21.1

Reference genome

Start

End

47684812/47392615 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-3662 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4506 ; hsa-mir-7-5p ; hsa-mir-5003-5p ; hsa-mir-8485 ; hsa-mir-3529-3p ; hsa-mir-589-3p ; hsa-mir-8068 ; hsa-mir-1225-5p ; hsa-mir-10b-3p ; hsa-mir-1278 ; hsa-mir-1911-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3182 ; hsa-mir-361-5p ; hsa-mir-3617-3p ; hsa-mir-374a-3p ; hsa-mir-4303 ; hsa-mir-4490 ; hsa-mir-452-5p ; hsa-mir-4659a-3p ; hsa-mir-4659b-3p ; hsa-mir-4676-3p ; hsa-mir-4682 ; hsa-mir-513a-5p ; hsa-mir-6736-3p ; hsa-mir-892c-3p ; hsa-mir-4433a-3p ; hsa-mir-4433b-3p ; hsa-mir-4496 ; hsa-mir-4722-5p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-6165

Nearest miRNA

hsa-mir-10393/Upstream/1959486; hsa-mir-11181/Downstream/1776455;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/207313, chr15-CpG: 129/Downstream/324606

Upstream sequence

cagaagcttaagaaaatagaatcatagaatcagtggtgacatactgtgatttgaattcatgtttatctgaaccgaaatcacaggccctttccaacacaat

Downstream sequence

acagccctgctgacatcttgagttagccctgtgaaatttctgggctaaaattctgacttctgacttccagaagtcgaagataataaatcttgttggtttt