Basic Information
VIS ID
TVIS20000143
Fusion event
HPV-chr20:q13.2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Cervical carcinoma (CC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26735580
Virus Sequence
Virus name
HPV
Subtype
HPV58
Reference genome
NC_001357.1
Region type
L1
Start
6833
Integrated sequence
CAATATGTGCT TCTACACAGTCTCCTGTACCTGGGCAATATGATGCTACCAAATTTAAGCAGTATAGCAGACATGTTGAGG AATATGATTTGCAGTTT| |ATTTTTCAGTTGTGTACTATTACTTTAACTGCAGATGTTATGTCCTATATTCA TAGTATGAATAGCAGTATTTTAGAGGATTGGAACTTTGGTGTTCCC
Host Sequence
Chromosome
chr20
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
53615729/54999190 (Hg38)
End
53615729/54999190 (Hg38)
Nearest miRNA
hsa-mir-103a-2/Upstream/930705; hsa-mir-1-1/Downstream/2322312;
Nearest TSS
ENST00000382410/Upstream/444257; ENST00000608080/Downstream/409708;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/522736, chr20-CpG: 165/Downstream/1004357
Upstream sequence
gcctcggtctctctgggattacagacgtgagccactgtgccctgccAATGTAGTTTTTAATCGTTATTTTTTTTTTCTGAAACATTGAAGTTGTGGAAAA
Downstream sequence
ctcatcagtttctgaatactttcttacttcttggcaagaaatgtgttcaaaaatcaccttacattttttgtttctagccacagaatcaatcTGATACTAG
Reference
Liu, Y., et al. Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology. Oncotarget,2016, 7(5): 5852-5864.
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