Basic Information
VIS ID
TVIS20000152
Fusion event
HPV-chr1:p36.21 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr1
Cytoband
p36.21
Reference genome
GRCh37/hg19
Start
15654620/15328124 (Hg38)
End
15654620/15328124 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
FHAD1 ; LOC101927417
Nearest miRNA
hsa-mir-12136/Upstream/2749101; hsa-mir-101-1/Downstream/1530825;
Nearest TSS
ENST00000473358/Upstream/1004; ENST00000532408/Downstream/7340;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/80667, chr1-CpG: 127/Downstream/81430
Upstream sequence
AATTCATCCAGTCTCAAACTGGGCATTCATTTAAATCTATTGTCTTAGATGGAGATATCTAGTATACTCACTCATTTAAAGTAGAGCCGTAAATCCTGAA
Downstream sequence
aagattcaaagactgggatgacttagttggaatcatctatgagccagttcattcacataactggtggttgacccatgctgtcagctagaacctgaagctg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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