Basic Information
VIS ID
TVIS20000165
Fusion event
HPV-RAD52 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
1037639/928473 (Hg38)
End
1037639/928473 (Hg38)
Location type
Intronic
Target gene
RAD52
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-373-3p ; hsa-mir-607 ; hsa-mir-3671
Nearest miRNA
hsa-let-7i/Downstream/731842;
Nearest TSS
ENST00000382841/Upstream/11891; ENST00000587595/Downstream/4585;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/174226, chr12-CpG: 78/Downstream/20842
Upstream sequence
TTGATGTCCCTGAGGACTCTGATGACTGCATTCCCATGTGGCCAgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtACATGCAACAAT
Downstream sequence
acatgatacaatatgaatgagccttgtgtgtgagtctgtttgtacaaaatgtccagaataggcaaatctattctgacagaactagagacagaaggcagat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate