Fusion event
HPV-chr21:q22.11 integration
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reference genome
NC_001526.2;AY262282.1;EF202167.1
End
33996659/32624349 (Hg38)
Nearest miRNA
hsa-let-7c/Upstream/2248971; hsa-mir-3197/Downstream/926313;
Upstream sequence
TTACATATTTTACAGGGTCTCaatataatttttaataatattGAGAAATGTAGAAAATCGTTGCATAAGAACCCATGTACTGACCATCCAGTTTTGTTTA
Downstream sequence
AATATGTAGGTTAGTAATCATCTAGTGATTATTAAAATCACCACAGATCAAGCCTGTGCAGTATCTTTAAATTTGTCAGCCCTGGTATTCGTTGTCCTCA
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.