Basic Information
VIS ID
TVIS20000194
Fusion event
HPV-chr6:p22.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;EF202167.1
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
End
25222119/25221891 (Hg38)
Fragile sites / regions
Nearest miRNA
hsa-mir-3691/Upstream/6650011; hsa-mir-10398/Downstream/1925735;
Nearby gene
LOC100533655(-723) ;
Upstream sequence
AATTGGTCTGTGTGCCTGTGTAGAGATATACAACCTCAGGAAACCAAAGAACAAATCTGGACTCACACTGTCCCAGGTTCTATAAGGTACATAGGGTAAG
Downstream sequence
TTATTACAATATAGCCAGATAATATGGTTCATATAACTTAGATTCTTAAACATTTTGACTTTAAAGACTTTCTTTGTgacctagtacctggagcaggagt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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