Fusion event
HPV-chr6:p22.2 integration
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reference genome
NC_001526.2;AY262282.1;EF202167.1
End
25222119/25221891 (Hg38)
Nearest miRNA
hsa-mir-3691/Upstream/6650011; hsa-mir-10398/Downstream/1925735;
Upstream sequence
AATTGGTCTGTGTGCCTGTGTAGAGATATACAACCTCAGGAAACCAAAGAACAAATCTGGACTCACACTGTCCCAGGTTCTATAAGGTACATAGGGTAAG
Downstream sequence
TTATTACAATATAGCCAGATAATATGGTTCATATAACTTAGATTCTTAAACATTTTGACTTTAAAGACTTTCTTTGTgacctagtacctggagcaggagt
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.