Basic Information
VIS ID
TVIS20000198
Fusion event
HPV-AGTRAP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
End
11798683/11738626 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-125a-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-155-5p ; hsa-mir-377-5p ; hsa-mir-766-3p ; hsa-mir-940 ; hsa-mir-3681-3p ; hsa-mir-6086 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6733-3p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3942-3p ; hsa-mir-3915 ; hsa-mir-5100 ; hsa-mir-1294 ; hsa-mir-7160-5p ; hsa-mir-655-5p ; hsa-mir-1827 ; hsa-mir-3928-3p ; hsa-mir-4649-3p ; hsa-mir-1250-3p ; hsa-mir-1245b-3p ; hsa-mir-5582-5p ; hsa-mir-6749-3p ; hsa-mir-6069 ; hsa-mir-4469 ; hsa-mir-532-3p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-660-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-662 ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6820-5p ; hsa-mir-4660 ; hsa-mir-6849-3p ; hsa-mir-6736-3p ; hsa-mir-3614-3p ; hsa-mir-7108-5p ; hsa-mir-6818-3p ; hsa-mir-6873-3p ; hsa-mir-663b ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-874-5p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-513b-5p ; hsa-mir-3165 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4736 ; hsa-mir-3665 ; hsa-mir-6089 ; hsa-mir-383-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-624-3p ; hsa-mir-3974 ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4668-5p ; hsa-mir-616-5p ; hsa-mir-6827-3p
Nearest miRNA
hsa-mir-12136/Upstream/1771168; hsa-mir-101-1/Downstream/290532;
Upstream sequence
ctccgtcgcaaaaaaaaaaaaaagaaaagaaaaaagaaaagaGAATCTCTGATTCTGGGACTCATTCCCTGGTGACAGGACCAACGTCCCCCTTGACAGC
Downstream sequence
CATCACCAAGACATATCAGGACCTCTGTCCTCCCGTGCTTAGACAGGGACTTAAGTTGCATCTCTCCCCTCTCCCATTCCCCTTCCCTCAGGGCCCCCCA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate