Basic Information
VIS ID
TVIS20000199
Fusion event
HPV-chr1:p31.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
67549144/67083461 (Hg38)
End
67549144/67083461 (Hg38)
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/454944; hsa-mir-11399/Downstream/1100057;
Nearest TSS
ENST00000473358/Upstream/29362; ENST00000637002/Downstream/43800;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/29005, chr1-CpG: 27/Downstream/51246
Nearby gene
C1orf141(+8715) ;
Upstream sequence
gaaaagaGAATCTCTGATTCTGGGACTCATTCCCTGGTGACAGGACCAACGTCCCCCTTGACAGCCATCACCAAGACATATCAGGACCTCTGTCCTCCCG
Downstream sequence
TGCTTAGACAGGGACTTAAGTTGCATCTCTCCCCTCTCCCATTCCCCTTCCCTCAGGGCCCCCCACCCCTGTATGTTACATCttttttttttttttcctt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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