Basic Information
VIS ID
TVIS20000207
Fusion event
HPV-SYT16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
62521303/62054585 (Hg38)
End
62521303/62054585 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
SYT16
Nearest miRNA
hsa-mir-208a/Upstream/1405874; hsa-mir-1185-1/Downstream/2040439;
Nearest TSS
ENST00000550708/Upstream/58751; ENST00000430451/Downstream/24762;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/189662, chr14-CpG: 25/Downstream/2272
Upstream sequence
ACACTATGCCCTAGGACTATACAGTCTTCCTTTATCTATATgcatgctgtatgtcagaaaagagttttcatttgtggatttaattgctcgtgaatcaact
Downstream sequence
tcctggactcaggtgatgtgcctgccttggcctcccaaagtgctgggattacagatgtgagccactgtgcctggcTAGTGAGTCTATTCTTAATATTCAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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