Basic Information
VIS ID
TVIS20000252
Fusion event
HPV-ABHD3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
19256606/21676645 (Hg38)
End
19256606/21676645 (Hg38)
Location type
Intronic
Target gene
ABHD3
miRNAs that regulate target gene
hsa-mir-221-3p
Nearest miRNA
hsa-mir-3156-2/Upstream/6846403; hsa-mir-1-2/Downstream/6873;
Nearest TSS
ENST00000575820/Upstream/3017; ENST00000577749/Downstream/27043;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/64012, chr18-CpG: 75/Downstream/27559
Upstream sequence
cccaaaggccacacctcccaatactatcagactggaggttaagatttggatatatgtattttgggaggacacaaacattcagtccataacGTATGTCTAT
Downstream sequence
ctcccaaagtgctgggattacccgcataagccaccgcatccggccTTAAgttggctgacattctatctcagctccttatcttgtctgggactagagtcag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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