Basic Information
VIS ID
TVIS20000256
Fusion event
HPV-FAM157A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
197900757/198173886 (Hg38)
End
197900757/198173886 (Hg38)
Location type
Intronic
Target gene
FAM157A
Nearest miRNA
hsa-let-7g/Upstream/499310;
Nearest TSS
ENST00000440867/Upstream/134652;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/16405, None/Downstream
Upstream sequence
GAATACTGCAAAGAAAAATGAGGAGGATTACAGTACTAGATACTTCAGTCCGGCAACTCTGAAATGAGCTGTGAACATAACAACAGACTCAAGGGTGGAA
Downstream sequence
ggttagggttagggttagggttagggttagggttagggttagggttagggttagggttaggggtgtgggtgagggtgaggatgaaggttaagggttaggt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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