Basic Information
VIS ID
TVIS20000259
Fusion event
HPV-chr1:p32.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
54386152/53920479 (Hg38)
End
54386152/53920479 (Hg38)
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/2084077; hsa-mir-101-1/Downstream/133600;
Nearest TSS
ENST00000473358/Upstream/26268; ENST00000371368/Downstream/8521;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/30496, chr1-CpG: 142/Downstream/24905
Nearby gene
DIO1(-9393) ; HSPB11(+1082) ;
Upstream sequence
TGCCCAATCTAGTCCACTTCCCACATCACTAAACAAGGCAgcagagtttctccgagataagaggcagacttggagtccaacagatagggcttagggttca
Downstream sequence
agcccacctctgtccctgagtgagcctcagtaggtgactttacctctgtcgcaggtttctcaacaacagcaccaataacggtaacaacaggacctgcttc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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