Basic Information
VIS ID
TVIS20000279
Fusion event
HPV-ZBED5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
10877648/10856101 (Hg38)
End
10877648/10856101 (Hg38)
Location type
Intronic
Target gene
ZBED5
Nearest miRNA
hsa-mir-210/Upstream/347775; hsa-let-7a-2/Downstream/800550;
Nearest TSS
ENST00000527297/Upstream/29519; ENST00000529014/Downstream/117;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/46527, chr11-CpG: 97/Downstream/1454
Upstream sequence
aattatgtgtcttggagttgctcttctcgaggagtatctttgtggtgttctctgtatttcctgaatctgaacgttggcctgccttgctaggttggggaag
Downstream sequence
ttctcctggataatatcctgcagagtgttttccaacttggttccattctccgcatcactttcagctacaccaatcagacgtaaatttggtcttttcacat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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