Basic Information
VIS ID
TVIS20000287
Fusion event
HPV-MAPKAPK5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr12
Cytoband
q24.12
Reference genome
End
112299649/111861845 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-4517 ; hsa-mir-6771-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p ; hsa-mir-6818-3p ; hsa-mir-6895-3p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-4452 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4795-5p ; hsa-mir-494-3p ; hsa-mir-4635 ; hsa-mir-602 ; hsa-mir-377-3p ; hsa-mir-4789-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-3977 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-5693 ; hsa-mir-383-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3922-5p ; hsa-mir-6814-5p ; hsa-mir-653-3p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6087 ; hsa-mir-4459 ; hsa-mir-7846-3p ; hsa-mir-665 ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-4683 ; hsa-mir-7160-5p ; hsa-mir-7854-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-4509 ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-3910 ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-4484 ; hsa-mir-6768-3p ; hsa-mir-548an ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-335-5p ; hsa-mir-3612 ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-455-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6807-5p ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-215-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-4466 ; hsa-mir-454-3p ; hsa-mir-500b-3p ; hsa-mir-504-3p ; hsa-mir-5691 ; hsa-mir-675-5p ; hsa-mir-6773-3p ; hsa-mir-6805-3p ; hsa-mir-6879-3p ; hsa-mir-1228-5p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-4728-5p ; hsa-mir-548a-3p ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548ar-3p ; hsa-mir-548av-3p ; hsa-mir-548az-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-6089 ; hsa-mir-6134 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-653-5p
Nearest miRNA
hsa-let-7i/Upstream/61940; hsa-mir-1178/Downstream/175754;
Upstream sequence
ttttactaagtgatttttagcagatatgggctttgaattttgtctagcacctttcatcctatctggagatattcttatgagttttctccttagatatatt
Downstream sequence
aacatagtaaaatattttaataaaatatctaatactgtaccatcctagcattcttcaattgtttatattaaaatatttttgtttgcccgtgcaattatat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate