Basic Information
VIS ID
TVIS20000294
Fusion event
HPV-LOC105370673 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr14
Cytoband
q32.31
Reference genome
GRCh37/hg19
Start
102000281/101533944 (Hg38)
End
102000281/101533944 (Hg38)
Location type
Intronic
Target gene
LOC105370673
Nearest miRNA
hsa-mir-1185-1/Upstream/467143; hsa-mir-12121/Downstream/26343;
Nearest TSS
ENST00000550708/Upstream/86302; ENST00000510508/Downstream/21732;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/7349, chr14-CpG: 456/Downstream/25708
Upstream sequence
TAAATTTTTGTTAGAATTTTAGAAAGGCTGAAACTAGAAAATGATTTTTTAAGAAGTTTTTAAAATCACCAGTTTAACATGTATTGTACACTCACTGTGT
Downstream sequence
CCAGCCCCGGCCTAGGAGTGCTAGCCCTTGAGGGCGTGACCTTAGCCAAGGCCCAGATCACCTTAAAACTCAGGACTGGGGGTGGGGGGGGCACTGGGCC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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