Basic Information
VIS ID
TVIS20000305
Fusion event
HPV-LINC02169 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
54291966/54258054 (Hg38)
End
54291966/54258054 (Hg38)
Location type
Intronic
Target gene
LINC02169
Nearest miRNA
hsa-mir-1225/Upstream/3515677; hsa-mir-11401/Downstream/1987466;
Nearest TSS
ENST00000527434/Upstream/18361; ENST00000637770/Downstream/12692;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/63487, chr16-CpG: 621/Downstream/23636
Upstream sequence
CaaaaaaaaaaaaaaaaaaacagaaaaaaaaaagaaaaaaaaCAGCATCGTCTGTGGGATTCTCCCTCAATGTCTGTTCCGTGAAAGATGCATTTTGTCC
Downstream sequence
TTCTCCTGGACATTTCCCGTGGAGCCGGCGGCCATCACTCCAACTGGTCCCCAAGTGGGGAGGGCCCTATACTGGTTCAGAACTATGAGAATGCACCTCA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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