Basic Information
VIS ID
TVIS20000330
Fusion event
HPV-CCDC148 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
159299545/158443033 (Hg38)
End
159299545/158443033 (Hg38)
Location type
Intronic
Target gene
CCDC148
Nearest miRNA
hsa-mir-128-1/Upstream/7074622; hsa-mir-10b/Downstream/743802;
Nearest TSS
ENST00000437798/Upstream/62073; ENST00000479398/Downstream/13533;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/566200, chr2-CpG: 169/Downstream/13627
Upstream sequence
GGAGTGGGGAATACCTTTTCCTTTCAAACCTTTTTTCTTTACCCATTATAACTAGAGGATCACCACTCACTATGTTGTCTTATAAATTATTCCTATAAGA
Downstream sequence
TtttgtttgtttgtttgtttgtttgtttTTTAATAAACAGCTGCTCCCTTGTTAAGGTAGGGGTAAGGTCCTAGAGTTAGGGACAGGAAGGCAAGATATA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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