Basic Information
VIS ID
TVIS20000333
Fusion event
HPV-ZNF804A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
185559029/184694302 (Hg38)
End
185559029/184694302 (Hg38)
Location type
Intronic
Target gene
ZNF804A
miRNAs that regulate target gene
hsa-mir-137
Nearest miRNA
hsa-mir-10b/Upstream/315258; hsa-mir-1244-1/Downstream/3603190;
Nearest TSS
ENST00000437798/Upstream/95294; ENST00000613975/Downstream/172063;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/95440, chr2-CpG: 53/Downstream/1044363
Upstream sequence
CAGTCCTGTTTTGATATTGGGGCCTAGAAAATAGGCTTCAATTTGCTGAAGAGTTAGTGATGATAAAGAAACATTGTGCCTAATTAATACTGTAAAAAGT
Downstream sequence
ATAAAAATTTCAGTGTCAAATGGAGACCACCACAAATTGTTCTTTCACAAATCTTGTTCGCTTGTCCATGGATGATTTATTTTAGGAGCTTGGTTTTTAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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