Basic Information
VIS ID
TVIS20000343
Fusion event
HPV-FAM230F integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
18874404/18886891 (Hg38)
End
18874404/18886891 (Hg38)
Location type
Intronic
Target gene
FAM230F
Nearest miRNA
hsa-mir-3198-1/Upstream/905930; hsa-let-7a-3/Downstream/1076862;
Nearest TSS
ENST00000624155/Upstream/130543; ENST00000608842/Downstream/7516;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/13242, chr22-CpG: 102/Downstream/18847
Upstream sequence
TGGTAAAATACACCTCCTCCATCCCCAAGGAAATATTATCTAACATCTATAATGTAGTGGATAATTTTCCCATAGCTGATATCAACTGAAAAATAAAGGA
Downstream sequence
TCCAAGAAAACAACATTTACATCTTAGGCAAAGACAGGCTACTTTACCTTGGTAGTAGAGTAGGGCTGCCTTTTCACACGCCTTTGGGAAGGCTTCTTCG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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