Basic Information
VIS ID
TVIS20000345
Fusion event
HPV-LOC105376921 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
GRCh37/hg19
Start
107669/65986 (Hg38)
End
107669/65986 (Hg38)
Location type
Intronic
Target gene
LOC105376921
Nearest miRNA
hsa-let-7g/Downstream/5184191;
Nearest TSS
ENST00000440867/Upstream/11640; ENST00000486881/Downstream/130610;
Nearest CpG islands
None/Target, None/Upstream, chr3-CpG: 148/Downstream/130722
Upstream sequence
aggccaaatgaagcaaacagttatgtgggtgcaagccaaagaatgcttggggccaccagaagctagaagaggcaaggaagttttctcccctagagcctgt
Downstream sequence
gattcaaaacatagatctgtctgagtccaaaagccttcatcttGGCAGTGGAATATAGTCAATGGCTAAGAGACAAGAAACAATGGAGAGCTTAGAACTA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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