Basic Information
VIS ID
TVIS20000367
Fusion event
HPV-LINC02484 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
34185947/34184325 (Hg38)
End
34185947/34184325 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
LINC02484
Nearest miRNA
hsa-mir-12113/Upstream/5364657; hsa-mir-1243/Downstream/2242041;
Nearest TSS
ENST00000502981/Upstream/144432; ENST00000514737/Downstream/74802;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/3461105, chr4-CpG: 100/Downstream/2059684
Upstream sequence
tcaaaagtttgagaccagcctgggcaacatagcaagaccctatctctctataaaatttaaaaaataataaaaaattagccgggtgtggtacatgcctgta
Downstream sequence
CACTGAAGTGCCCTGTAGGAATACAATTGAGCTTTCCTACCTTGCACTAGGTTTCAGGGGCTGCCACTTTGCAATAGAATACCAGTATGGCTGAAAACAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate