Basic Information
VIS ID
TVIS20000369
Fusion event
HPV-LINC01258 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
38424636/38423015 (Hg38)
End
38424636/38423015 (Hg38)
Location type
Intronic
Target gene
LINC01258
Nearest miRNA
hsa-mir-12113/Upstream/1181024; hsa-mir-1243/Downstream/445017;
Nearest TSS
ENST00000502981/Upstream/56101; ENST00000507056/Downstream/86752;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/408195, chr4-CpG: 164/Downstream/240013
Upstream sequence
agttgtgtggttttgagtgagtttcttaatcctgaattctaatttgattgcactgtggtctgaaagactgttcttataatttcagttcttttgcatttgc
Downstream sequence
agcgtgtggcatgaaggaagtgcccaataaacacatgctgaatATCTACTGCTTGTCCGCAAATAAGAATTAAGTGCCTGGAAACCCAAACAGGGGCAGA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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