Basic Information
VIS ID
TVIS20000370
Fusion event
HPV-TEC integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr4
Cytoband
p11
Reference genome
GRCh37/hg19
Start
48203303/48201286 (Hg38)
End
48203303/48201286 (Hg38)
Location type
Intronic
Target gene
TEC
Nearest miRNA
hsa-mir-12113/Upstream/548543; hsa-mir-1243/Downstream/4511396;
Nearest TSS
ENST00000502981/Upstream/45420; ENST00000506375/Downstream/27373;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/183864, chr4-CpG: 49/Downstream/68059
Nearest cancer related gene
TEC(OG, No orient, 0)
Upstream sequence
catcctgtcacgaagatgtggatgtttattttttctttaatgattagaaaaaattagaaaacccagatgacctctcaaattacatgatgaaattataata
Downstream sequence
tttcagacatttgaatttgagatacctgtgagaactcagacctcagaatagatatcaggctgggaaacaaagactgggaaagtcatctgcacacagaagt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate