Basic Information
VIS ID
TVIS20000373
Fusion event
HPV-LINC01088 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
80014494/79093340 (Hg38)
End
80014494/79093340 (Hg38)
Location type
Intronic
Target gene
LINC01088
Nearest miRNA
hsa-mir-12113/Upstream/2517714; hsa-mir-1243/Downstream/3659997;
Nearest TSS
ENST00000502981/Upstream/8101; ENST00000511895/Downstream/102494;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/153749, chr4-CpG: 39/Downstream/871350
Upstream sequence
agcactatttattgaaatcctttcccaattgcttgcttttgctcagccttgccaaagatcaggtgactgtaggtgtgcagctttatctctgagttttctg
Downstream sequence
CTACCAAAGTTTTGGCTCCGATTAAGGAAGGGGAATAGAAAACTCATTCTATACCCTTTGATTTCCTTTTTTCGATTATTGTTTAACAGGAAATAGAGCT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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