Basic Information
VIS ID
TVIS20000385
Fusion event
HPV-ZNF165 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
28068019/28100241 (Hg38)
End
28068019/28100241 (Hg38)
Location type
Intronic
Target gene
ZNF165
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-3143/Upstream/952553; hsa-mir-10398/Downstream/2484091;
Nearest TSS
ENST00000381078/Upstream/19111; ENST00000340487/Downstream/24319;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/206424, chr6-CpG: 43/Downstream/4445
Upstream sequence
GGTGAGAAAATTCCTGACTCACAAATGACtctgtgaaaaatgaggataagaatgcccagttcatagagagctatgataattacatgaaacacggtattta
Downstream sequence
ttggagtatctgaaaatgataggaagattggaaccaagttggaaaacacacttcaggatatcatccaggagaacttccccaacctagcaagacaggccaa
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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