Basic Information
VIS ID
TVIS20000393
Fusion event
HPV-PDE1C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
31999277/31959665 (Hg38)
End
31999277/31959665 (Hg38)
Location type
Intronic
Target gene
PDE1C
Nearest miRNA
hsa-mir-1183/Upstream/1669775; hsa-mir-10399/Downstream/773316;
Nearest TSS
ENST00000635602/Upstream/80381; ENST00000645498/Downstream/111184;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/622737, chr7-CpG: 70/Downstream/110786
Upstream sequence
ttttgagtgtggatgtccagtttccccgaaaccatttaaagagacggctcttaccccagagtctgcttcacacctagttgaccatatatggtcaggttta
Downstream sequence
agattttcaaacatagactagaatgaaaataaagtttccaattgtttaaagaactctgtccctattatgcttcttaaggaggagaataggtgccaaatca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate